Read data

source(paste0(root.dir, "scripts/myRLib.R"))
funcset <- readLines(paste0(root.dir, "output-run_step2/fastInsulin__wtccc_t2d__wtccc_ctrl/func_subset.set"))
funcset <- parseFuncSet(funcset)
funcset.names <- names(funcset)
xtyi.files <- strsplit("output-direction_XT_YI/fastInsulin__wtccc_t2d__wtccc_ctrl/xtyi_LDpred_p1.0000e+00.assoc.logistic:output-direction_XT_YI/fastInsulin__wtccc_t2d__wtccc_ctrl/xtyi_LDpred_p3.0000e-01.assoc.logistic:output-direction_XT_YI/fastInsulin__wtccc_t2d__wtccc_ctrl/xtyi_LDpred_p1.0000e-01.assoc.logistic:output-direction_XT_YI/fastInsulin__wtccc_t2d__wtccc_ctrl/xtyi_LDpred_p3.0000e-02.assoc.logistic:output-direction_XT_YI/fastInsulin__wtccc_t2d__wtccc_ctrl/xtyi_LDpred_p1.0000e-02.assoc.logistic:output-direction_XT_YI/fastInsulin__wtccc_t2d__wtccc_ctrl/xtyi_LDpred_p3.0000e-03.assoc.logistic:output-direction_XT_YI/fastInsulin__wtccc_t2d__wtccc_ctrl/xtyi_LDpred_p1.0000e-03.assoc.logistic:output-direction_XT_YI/fastInsulin__wtccc_t2d__wtccc_ctrl/xtyi_LDpred_p3.0000e-04.assoc.logistic:output-direction_XT_YI/fastInsulin__wtccc_t2d__wtccc_ctrl/xtyi_LDpred_p1.0000e-04.assoc.logistic", 
    ":")[[1]]
ps <- strsplit("1,0.3,0.1,0.03,0.01,0.003,0.001,0.0003,0.0001", 
    ",")[[1]]
inter.files <- strsplit("output-run_step2/fastInsulin__wtccc_t2d__wtccc_ctrl/interaction.func_subset_LDpred_p1.0000e+00.assoc.logistic:output-run_step2/fastInsulin__wtccc_t2d__wtccc_ctrl/interaction.func_subset_LDpred_p3.0000e-01.assoc.logistic:output-run_step2/fastInsulin__wtccc_t2d__wtccc_ctrl/interaction.func_subset_LDpred_p1.0000e-01.assoc.logistic:output-run_step2/fastInsulin__wtccc_t2d__wtccc_ctrl/interaction.func_subset_LDpred_p3.0000e-02.assoc.logistic:output-run_step2/fastInsulin__wtccc_t2d__wtccc_ctrl/interaction.func_subset_LDpred_p1.0000e-02.assoc.logistic:output-run_step2/fastInsulin__wtccc_t2d__wtccc_ctrl/interaction.func_subset_LDpred_p3.0000e-03.assoc.logistic:output-run_step2/fastInsulin__wtccc_t2d__wtccc_ctrl/interaction.func_subset_LDpred_p1.0000e-03.assoc.logistic:output-run_step2/fastInsulin__wtccc_t2d__wtccc_ctrl/interaction.func_subset_LDpred_p3.0000e-04.assoc.logistic:output-run_step2/fastInsulin__wtccc_t2d__wtccc_ctrl/interaction.func_subset_LDpred_p1.0000e-04.assoc.logistic", 
    ":")[[1]]
prs.files <- strsplit("../step1/output-run_step1/fastInsulin__wtccc_t2d__wtccc_ctrl/ldpred_LDpred_p1.0000e+00.txt:../step1/output-run_step1/fastInsulin__wtccc_t2d__wtccc_ctrl/ldpred_LDpred_p3.0000e-01.txt:../step1/output-run_step1/fastInsulin__wtccc_t2d__wtccc_ctrl/ldpred_LDpred_p1.0000e-01.txt:../step1/output-run_step1/fastInsulin__wtccc_t2d__wtccc_ctrl/ldpred_LDpred_p3.0000e-02.txt:../step1/output-run_step1/fastInsulin__wtccc_t2d__wtccc_ctrl/ldpred_LDpred_p1.0000e-02.txt:../step1/output-run_step1/fastInsulin__wtccc_t2d__wtccc_ctrl/ldpred_LDpred_p3.0000e-03.txt:../step1/output-run_step1/fastInsulin__wtccc_t2d__wtccc_ctrl/ldpred_LDpred_p1.0000e-03.txt:../step1/output-run_step1/fastInsulin__wtccc_t2d__wtccc_ctrl/ldpred_LDpred_p3.0000e-04.txt:../step1/output-run_step1/fastInsulin__wtccc_t2d__wtccc_ctrl/ldpred_LDpred_p1.0000e-04.txt", 
    ":")[[1]]

Epistasis

for (i in 1:length(xtyi.files)) {
    cat("##", funcset.names[i])
    cat("
")
    cat("
")
    snp.subset <- funcset[[funcset.names[i]]]
    
    # read I ~ SNP
    prs <- read.table(paste0(root.dir, prs.files[i]), header = T)
    prs$sid <- as.character(prs$sid)
    prs.sub <- prs[prs$sid %in% snp.subset, ]
    
    # read others
    xtyi <- read.table(paste0(root.dir, xtyi.files[i]), header = T)
    xtyi$SNP <- as.character(xtyi$SNP)
    yt.xtyi <- xtyi[(xtyi$SNP %in% snp.subset) & (xtyi$SNP %in% 
        prs.sub$sid), ]
    yt.xtyi.xt <- yt.xtyi[yt.xtyi$TEST == "ADD", ]
    yt.xtyi.yi <- yt.xtyi[yt.xtyi$TEST == "PRS", ]
    inter <- read.table(paste0(root.dir, inter.files[i]), header = T)
    inter$SNP <- as.character(inter$SNP)
    inter <- inter[inter$TEST == "ADDxPRS", ]
    yt.inter <- inter[(inter$SNP %in% snp.subset) & (inter$SNP %in% 
        prs.sub$sid), ]
    
    # order all rows
    yt.xtyi.xt <- yt.xtyi.xt[order(yt.xtyi.xt$SNP), ]
    yt.xtyi.yi <- yt.xtyi.yi[order(yt.xtyi.yi$SNP), ]
    yt.inter <- yt.inter[order(yt.inter$SNP), ]
    prs.sub <- prs.sub[order(prs.sub$sid), ]
    
    # check direction
    prs.sub$nt1 <- as.character(prs.sub$nt1)
    yt.xtyi.xt$A1 <- as.character(yt.xtyi.xt$A1)
    yt.inter$A1 <- as.character(yt.inter$A1)
    if (sum(prs.sub$nt1 != yt.xtyi.xt$A1) != 0 | sum(prs.sub$nt1 != 
        yt.inter$A1) != 0) {
        print("Direction does not match. Exit!")
        quit()
    }
    
    yt.xtyi.xt.mean.std <- getMeanStd(yt.xtyi.xt$SNP, yt.xtyi.xt$P, 
        yt.xtyi.xt$OR, "Y~Gi+I (Gi)")
    yt.xtyi.yi.mean.std <- getMeanStd(yt.xtyi.yi$SNP, yt.xtyi.yi$P, 
        yt.xtyi.yi$OR, "Y~Gi+I (I)")
    yt.inter.mean.std <- getMeanStd(yt.inter$SNP, yt.inter$P, 
        yt.inter$OR, "Y~Gi*I")
    prs.sub.mean.std <- data.frame(SNP = prs.sub$sid, Mean = prs.sub$ldpred_beta, 
        Std = 0, Type = "I~Gi")
    
    # create data frame for plot
    df <- rbind(yt.xtyi.xt.mean.std, yt.xtyi.yi.mean.std, prs.sub.mean.std, 
        yt.inter.mean.std)
    ratio <- max(1, nrow(yt.inter)/30)
    cat
    p <- ggplot(df) + geom_point(aes(x = SNP, y = Mean)) + geom_errorbar(aes(x = SNP, 
        ymin = Mean - 1.96 * Std, ymax = Mean + 1.96 * Std), 
        colour = "black", width = 0.1) + geom_hline(yintercept = 0, 
        color = "red") + facet_grid(. ~ Type, scales = "free_x") + 
        coord_flip() + theme(axis.text.x = element_text(angle = 90, 
        hjust = 1))
    p2 <- ggplot(yt.inter) + geom_bar(aes(x = SNP, y = -log10(P)), 
        stat = "identity") + coord_flip() + ggtitle("Interaction P-value")
    subchunkify(p, ratio)
    subchunkify(p2, ratio)
    cat("
")
    pander(yt.inter[order(yt.inter$P, decreasing = F), ])
    cat("
")
    cat("
")
}

p1.0000e+00

  CHR SNP BP A1 TEST NMISS OR STAT P
150 8 rs11998620 0 T ADDxPRS 4862 0.7604 -2.17 0.03001
27 2 rs2943646 0 A ADDxPRS 4862 1.233 2.088 0.0368
30 2 rs2972147 0 T ADDxPRS 4862 1.232 2.081 0.03742
60 4 rs6855891 0 T ADDxPRS 4862 1.312 2.041 0.04128
18 2 rs2943634 0 A ADDxPRS 4862 1.223 2.01 0.04442
33 2 rs2972144 0 A ADDxPRS 4862 1.221 1.998 0.04574
186 17 rs17701598 0 A ADDxPRS 4862 1.256 1.992 0.04632
24 2 rs2943640 0 A ADDxPRS 4862 1.213 1.925 0.05418
39 2 rs1515099 0 G ADDxPRS 4862 1.207 1.903 0.05701
66 4 rs1835523 0 G ADDxPRS 4862 1.277 1.854 0.06375
105 5 rs255761 0 T ADDxPRS 4862 1.238 1.843 0.06534
129 6 rs3800426 0 T ADDxPRS 4862 0.8379 -1.842 0.06547
63 4 rs11947970 0 T ADDxPRS 4862 1.272 1.819 0.06884
42 2 rs2673140 0 G ADDxPRS 4862 1.197 1.808 0.07067
36 2 rs2943658 0 A ADDxPRS 4862 1.194 1.782 0.07471
9 1 rs7543693 0 T ADDxPRS 4862 1.166 1.445 0.1483
156 11 rs2513726 0 G ADDxPRS 4862 1.151 1.346 0.1782
168 12 rs12313737 0 C ADDxPRS 4862 1.14 1.305 0.1919
12 1 rs2065914 0 C ADDxPRS 4862 0.8937 -1.205 0.2282
159 11 rs2441979 0 G ADDxPRS 4862 1.133 1.203 0.2291
51 3 rs11709077 0 A ADDxPRS 4862 0.832 -1.173 0.2409
189 18 rs512743 0 C ADDxPRS 4862 0.887 -1.171 0.2417
75 4 rs17811827 0 T ADDxPRS 4862 1.126 1.165 0.2439
78 4 rs17811863 0 A ADDxPRS 4862 1.124 1.143 0.2531
81 4 rs17206359 0 G ADDxPRS 4862 1.123 1.139 0.2545
3 1 rs7544694 0 G ADDxPRS 4862 1.126 1.139 0.2546
6 1 rs17606320 0 A ADDxPRS 4862 1.125 1.133 0.2571
99 5 rs6886510 0 T ADDxPRS 4862 1.128 1.121 0.2625
54 3 rs17036328 0 C ADDxPRS 4862 0.8413 -1.116 0.2645
102 5 rs6876198 0 C ADDxPRS 4862 1.124 1.087 0.2773
126 6 rs2049316 0 C ADDxPRS 4862 0.8511 -1.077 0.2816
108 5 rs6864348 0 G ADDxPRS 4862 0.8979 -1.015 0.3101
87 4 rs6827631 0 C ADDxPRS 4862 1.108 1.006 0.3143
147 7 rs1181736 0 A ADDxPRS 4862 1.122 0.9983 0.3182
132 7 rs11979110 0 T ADDxPRS 4862 1.099 0.9717 0.3312
72 4 rs10023994 0 A ADDxPRS 4862 1.101 0.9501 0.342
84 4 rs1469244 0 G ADDxPRS 4862 1.1 0.9392 0.3476
144 7 rs1181729 0 A ADDxPRS 4862 1.111 0.9141 0.3607
153 9 rs6560613 0 C ADDxPRS 4862 0.8639 -0.8559 0.392
117 6 rs16895362 0 T ADDxPRS 4862 0.8552 -0.8443 0.3985
48 3 rs2119812 0 T ADDxPRS 4862 0.8421 -0.8274 0.408
96 4 rs4691380 0 T ADDxPRS 4862 1.088 0.8265 0.4085
90 4 rs1364907 0 C ADDxPRS 4862 1.087 0.8144 0.4154
165 11 rs2155105 0 T ADDxPRS 4862 0.9316 -0.7488 0.454
93 4 rs10017970 0 G ADDxPRS 4862 1.08 0.748 0.4545
135 7 rs13230111 0 G ADDxPRS 4862 1.075 0.7464 0.4554
141 7 rs13233731 0 A ADDxPRS 4862 1.075 0.7464 0.4554
57 3 rs9860730 0 G ADDxPRS 4862 1.076 0.7107 0.4773
120 6 rs12173920 0 T ADDxPRS 4862 0.8786 -0.6973 0.4856
192 20 rs619289 0 T ADDxPRS 4862 1.094 0.6813 0.4957
45 3 rs7613596 0 T ADDxPRS 4862 1.065 0.6496 0.5159
198 20 rs856329 0 T ADDxPRS 4862 0.9362 -0.6172 0.5371
69 4 rs2139980 0 A ADDxPRS 4862 1.059 0.5724 0.5671
162 11 rs11236720 0 C ADDxPRS 4862 1.07 0.5309 0.5955
114 6 rs9368834 0 G ADDxPRS 4862 0.9336 -0.4267 0.6696
138 7 rs7810507 0 A ADDxPRS 4862 1.044 0.4039 0.6863
111 6 rs3734262 0 T ADDxPRS 4862 0.9474 -0.3364 0.7366
21 2 rs2943636 0 G ADDxPRS 4862 1.023 0.247 0.8049
180 13 rs7994634 0 T ADDxPRS 4862 1.024 0.2093 0.8342
195 20 rs6126646 0 T ADDxPRS 4862 0.9843 -0.1448 0.8849
174 13 rs9515905 0 G ADDxPRS 4862 0.9863 -0.123 0.9021
15 2 rs16982292 0 G ADDxPRS 4862 1.011 0.09557 0.9239
183 13 rs7989842 0 T ADDxPRS 4862 0.9908 -0.0821 0.9346
171 13 rs9523296 0 A ADDxPRS 4862 0.9917 -0.07379 0.9412
177 13 rs7986895 0 A ADDxPRS 4862 0.9935 -0.05769 0.954
123 6 rs1996913 0 C ADDxPRS 4862 0.9918 -0.04692 0.9626

p3.0000e-01

  CHR SNP BP A1 TEST NMISS OR STAT P
27 2 rs2943646 0 A ADDxPRS 4862 1.233 2.141 0.03229
30 2 rs2972147 0 T ADDxPRS 4862 1.23 2.114 0.03452
18 2 rs2943634 0 A ADDxPRS 4862 1.224 2.067 0.03874
33 2 rs2972144 0 A ADDxPRS 4862 1.218 2.021 0.04324
60 4 rs6855891 0 T ADDxPRS 4862 1.299 2.011 0.04433
150 8 rs11998620 0 T ADDxPRS 4862 0.7824 -2.009 0.04453
39 2 rs1515099 0 G ADDxPRS 4862 1.212 1.994 0.04619
24 2 rs2943640 0 A ADDxPRS 4862 1.211 1.954 0.05065
186 17 rs17701598 0 A ADDxPRS 4862 1.241 1.944 0.05189
42 2 rs2673140 0 G ADDxPRS 4862 1.203 1.908 0.05634
36 2 rs2943658 0 A ADDxPRS 4862 1.2 1.88 0.06015
66 4 rs1835523 0 G ADDxPRS 4862 1.261 1.799 0.07208
105 5 rs255761 0 T ADDxPRS 4862 1.22 1.763 0.07792
63 4 rs11947970 0 T ADDxPRS 4862 1.255 1.762 0.07809
129 6 rs3800426 0 T ADDxPRS 4862 0.8519 -1.715 0.08639
9 1 rs7543693 0 T ADDxPRS 4862 1.158 1.423 0.1546
168 12 rs12313737 0 C ADDxPRS 4862 1.14 1.35 0.1769
51 3 rs11709077 0 A ADDxPRS 4862 0.8317 -1.215 0.2245
3 1 rs7544694 0 G ADDxPRS 4862 1.13 1.21 0.2261
6 1 rs17606320 0 A ADDxPRS 4862 1.13 1.206 0.2278
12 1 rs2065914 0 C ADDxPRS 4862 0.8978 -1.194 0.2326
54 3 rs17036328 0 C ADDxPRS 4862 0.8369 -1.189 0.2344
99 5 rs6886510 0 T ADDxPRS 4862 1.123 1.106 0.2689
156 11 rs2513726 0 G ADDxPRS 4862 1.119 1.104 0.2696
102 5 rs6876198 0 C ADDxPRS 4862 1.12 1.08 0.2801
75 4 rs17811827 0 T ADDxPRS 4862 1.112 1.068 0.2856
165 11 rs2155105 0 T ADDxPRS 4862 0.9073 -1.056 0.2908
78 4 rs17811863 0 A ADDxPRS 4862 1.109 1.042 0.2972
147 7 rs1181736 0 A ADDxPRS 4862 1.123 1.037 0.2998
81 4 rs17206359 0 G ADDxPRS 4862 1.109 1.036 0.3
189 18 rs512743 0 C ADDxPRS 4862 0.9055 -0.9959 0.3193
159 11 rs2441979 0 G ADDxPRS 4862 1.103 0.9646 0.3347
87 4 rs6827631 0 C ADDxPRS 4862 1.099 0.9485 0.3429
144 7 rs1181729 0 A ADDxPRS 4862 1.109 0.92 0.3576
72 4 rs10023994 0 A ADDxPRS 4862 1.094 0.9057 0.3651
192 20 rs619289 0 T ADDxPRS 4862 1.122 0.8945 0.3711
84 4 rs1469244 0 G ADDxPRS 4862 1.092 0.8911 0.3729
153 9 rs6560613 0 C ADDxPRS 4862 0.8638 -0.8832 0.3771
96 4 rs4691380 0 T ADDxPRS 4862 1.087 0.8323 0.4052
108 5 rs6864348 0 G ADDxPRS 4862 0.9182 -0.8296 0.4067
117 6 rs16895362 0 T ADDxPRS 4862 0.8666 -0.7988 0.4244
126 6 rs2049316 0 C ADDxPRS 4862 0.8914 -0.7924 0.4281
90 4 rs1364907 0 C ADDxPRS 4862 1.082 0.7824 0.434
48 3 rs2119812 0 T ADDxPRS 4862 0.8558 -0.7801 0.4353
93 4 rs10017970 0 G ADDxPRS 4862 1.074 0.7135 0.4755
132 7 rs11979110 0 T ADDxPRS 4862 1.067 0.685 0.4933
198 20 rs856329 0 T ADDxPRS 4862 0.9338 -0.6584 0.5103
120 6 rs12173920 0 T ADDxPRS 4862 0.8889 -0.6555 0.5121
57 3 rs9860730 0 G ADDxPRS 4862 1.066 0.6375 0.5238
162 11 rs11236720 0 C ADDxPRS 4862 1.079 0.6157 0.5381
45 3 rs7613596 0 T ADDxPRS 4862 1.048 0.4996 0.6174
138 7 rs7810507 0 A ADDxPRS 4862 1.052 0.4867 0.6265
135 7 rs13230111 0 G ADDxPRS 4862 1.046 0.4778 0.6328
141 7 rs13233731 0 A ADDxPRS 4862 1.046 0.4778 0.6328
69 4 rs2139980 0 A ADDxPRS 4862 1.041 0.4098 0.6819
114 6 rs9368834 0 G ADDxPRS 4862 0.9579 -0.2753 0.7831
174 13 rs9515905 0 G ADDxPRS 4862 0.9745 -0.2378 0.812
183 13 rs7989842 0 T ADDxPRS 4862 0.9753 -0.2292 0.8187
21 2 rs2943636 0 G ADDxPRS 4862 1.021 0.2264 0.8209
171 13 rs9523296 0 A ADDxPRS 4862 0.9761 -0.2214 0.8248
177 13 rs7986895 0 A ADDxPRS 4862 0.9773 -0.2103 0.8334
111 6 rs3734262 0 T ADDxPRS 4862 0.9737 -0.1709 0.8643
15 2 rs16982292 0 G ADDxPRS 4862 0.9828 -0.1601 0.8728
195 20 rs6126646 0 T ADDxPRS 4862 0.9865 -0.1277 0.8984
180 13 rs7994634 0 T ADDxPRS 4862 1.01 0.09092 0.9276
123 6 rs1996913 0 C ADDxPRS 4862 1.015 0.08979 0.9285

p1.0000e-01

  CHR SNP BP A1 TEST NMISS OR STAT P
27 2 rs2943646 0 A ADDxPRS 4862 1.203 2.104 0.03537
39 2 rs1515099 0 G ADDxPRS 4862 1.194 2.048 0.0406
30 2 rs2972147 0 T ADDxPRS 4862 1.195 2.034 0.0419
18 2 rs2943634 0 A ADDxPRS 4862 1.195 2.03 0.04231
42 2 rs2673140 0 G ADDxPRS 4862 1.188 1.988 0.04677
36 2 rs2943658 0 A ADDxPRS 4862 1.183 1.941 0.05231
33 2 rs2972144 0 A ADDxPRS 4862 1.183 1.93 0.05366
24 2 rs2943640 0 A ADDxPRS 4862 1.179 1.876 0.0606
60 4 rs6855891 0 T ADDxPRS 4862 1.236 1.822 0.06851
186 17 rs17701598 0 A ADDxPRS 4862 1.186 1.731 0.0835
150 8 rs11998620 0 T ADDxPRS 4862 0.8435 -1.577 0.1148
66 4 rs1835523 0 G ADDxPRS 4862 1.196 1.554 0.1201
63 4 rs11947970 0 T ADDxPRS 4862 1.191 1.519 0.1289
165 11 rs2155105 0 T ADDxPRS 4862 0.8828 -1.515 0.1298
105 5 rs255761 0 T ADDxPRS 4862 1.164 1.508 0.1315
9 1 rs7543693 0 T ADDxPRS 4862 1.136 1.401 0.1612
3 1 rs7544694 0 G ADDxPRS 4862 1.133 1.395 0.163
6 1 rs17606320 0 A ADDxPRS 4862 1.133 1.392 0.1639
168 12 rs12313737 0 C ADDxPRS 4862 1.124 1.357 0.1749
129 6 rs3800426 0 T ADDxPRS 4862 0.8953 -1.327 0.1845
192 20 rs619289 0 T ADDxPRS 4862 1.16 1.279 0.2008
54 3 rs17036328 0 C ADDxPRS 4862 0.852 -1.217 0.2237
51 3 rs11709077 0 A ADDxPRS 4862 0.8541 -1.181 0.2374
12 1 rs2065914 0 C ADDxPRS 4862 0.9168 -1.085 0.278
147 7 rs1181736 0 A ADDxPRS 4862 1.112 1.069 0.2851
99 5 rs6886510 0 T ADDxPRS 4862 1.102 1.035 0.3008
102 5 rs6876198 0 C ADDxPRS 4862 1.101 1.023 0.3061
144 7 rs1181729 0 A ADDxPRS 4862 1.096 0.9178 0.3587
75 4 rs17811827 0 T ADDxPRS 4862 1.078 0.8441 0.3986
78 4 rs17811863 0 A ADDxPRS 4862 1.075 0.8147 0.4152
81 4 rs17206359 0 G ADDxPRS 4862 1.074 0.8046 0.4211
117 6 rs16895362 0 T ADDxPRS 4862 0.8809 -0.8022 0.4224
87 4 rs6827631 0 C ADDxPRS 4862 1.074 0.8023 0.4224
96 4 rs4691380 0 T ADDxPRS 4862 1.074 0.7997 0.4239
153 9 rs6560613 0 C ADDxPRS 4862 0.8889 -0.7987 0.4244
72 4 rs10023994 0 A ADDxPRS 4862 1.073 0.7865 0.4316
84 4 rs1469244 0 G ADDxPRS 4862 1.071 0.7655 0.444
162 11 rs11236720 0 C ADDxPRS 4862 1.087 0.7547 0.4504
15 2 rs16982292 0 G ADDxPRS 4862 0.9349 -0.6972 0.4857
90 4 rs1364907 0 C ADDxPRS 4862 1.063 0.6818 0.4954
120 6 rs12173920 0 T ADDxPRS 4862 0.8989 -0.6729 0.501
198 20 rs856329 0 T ADDxPRS 4862 0.9431 -0.6273 0.5305
138 7 rs7810507 0 A ADDxPRS 4862 1.059 0.6182 0.5365
93 4 rs10017970 0 G ADDxPRS 4862 1.057 0.6176 0.5368
48 3 rs2119812 0 T ADDxPRS 4862 0.8982 -0.6151 0.5385
156 11 rs2513726 0 G ADDxPRS 4862 1.053 0.5692 0.5692
183 13 rs7989842 0 T ADDxPRS 4862 0.9499 -0.5318 0.5949
177 13 rs7986895 0 A ADDxPRS 4862 0.9506 -0.524 0.6003
171 13 rs9523296 0 A ADDxPRS 4862 0.9507 -0.5223 0.6014
189 18 rs512743 0 C ADDxPRS 4862 0.9544 -0.5217 0.6019
57 3 rs9860730 0 G ADDxPRS 4862 1.047 0.5116 0.609
174 13 rs9515905 0 G ADDxPRS 4862 0.9553 -0.475 0.6348
159 11 rs2441979 0 G ADDxPRS 4862 1.041 0.4445 0.6566
108 5 rs6864348 0 G ADDxPRS 4862 0.9607 -0.4386 0.6609
123 6 rs1996913 0 C ADDxPRS 4862 1.037 0.2419 0.8089
126 6 rs2049316 0 C ADDxPRS 4862 0.9743 -0.2027 0.8394
180 13 rs7994634 0 T ADDxPRS 4862 0.9835 -0.1724 0.8631
45 3 rs7613596 0 T ADDxPRS 4862 1.011 0.1346 0.8929
21 2 rs2943636 0 G ADDxPRS 4862 1.011 0.1309 0.8958
132 7 rs11979110 0 T ADDxPRS 4862 1.011 0.1256 0.9
114 6 rs9368834 0 G ADDxPRS 4862 0.9835 -0.1196 0.9048
69 4 rs2139980 0 A ADDxPRS 4862 1.009 0.09811 0.9218
195 20 rs6126646 0 T ADDxPRS 4862 0.9932 -0.07091 0.9435
135 7 rs13230111 0 G ADDxPRS 4862 0.997 -0.03595 0.9713
141 7 rs13233731 0 A ADDxPRS 4862 0.997 -0.03595 0.9713
111 6 rs3734262 0 T ADDxPRS 4862 1.001 0.008163 0.9935

p3.0000e-02

  CHR SNP BP A1 TEST NMISS OR STAT P
165 11 rs2155105 0 T ADDxPRS 4862 0.8797 -1.816 0.06935
39 2 rs1515099 0 G ADDxPRS 4862 1.14 1.764 0.07767
42 2 rs2673140 0 G ADDxPRS 4862 1.138 1.744 0.08109
27 2 rs2943646 0 A ADDxPRS 4862 1.137 1.722 0.08501
36 2 rs2943658 0 A ADDxPRS 4862 1.131 1.656 0.09763
18 2 rs2943634 0 A ADDxPRS 4862 1.128 1.616 0.1062
30 2 rs2972147 0 T ADDxPRS 4862 1.127 1.605 0.1085
192 20 rs619289 0 T ADDxPRS 4862 1.173 1.584 0.1133
3 1 rs7544694 0 G ADDxPRS 4862 1.124 1.545 0.1223
6 1 rs17606320 0 A ADDxPRS 4862 1.124 1.542 0.1231
33 2 rs2972144 0 A ADDxPRS 4862 1.118 1.499 0.134
24 2 rs2943640 0 A ADDxPRS 4862 1.115 1.457 0.1451
60 4 rs6855891 0 T ADDxPRS 4862 1.149 1.387 0.1654
168 12 rs12313737 0 C ADDxPRS 4862 1.105 1.355 0.1754
15 2 rs16982292 0 G ADDxPRS 4862 0.8956 -1.33 0.1835
9 1 rs7543693 0 T ADDxPRS 4862 1.107 1.312 0.1896
186 17 rs17701598 0 A ADDxPRS 4862 1.11 1.247 0.2122
66 4 rs1835523 0 G ADDxPRS 4862 1.11 1.059 0.2895
63 4 rs11947970 0 T ADDxPRS 4862 1.108 1.034 0.3013
54 3 rs17036328 0 C ADDxPRS 4862 0.8925 -1.031 0.3027
105 5 rs255761 0 T ADDxPRS 4862 1.091 1.009 0.3128
51 3 rs11709077 0 A ADDxPRS 4862 0.8973 -0.9703 0.3319
117 6 rs16895362 0 T ADDxPRS 4862 0.889 -0.8761 0.381
147 7 rs1181736 0 A ADDxPRS 4862 1.077 0.873 0.3826
12 1 rs2065914 0 C ADDxPRS 4862 0.943 -0.8589 0.3904
162 11 rs11236720 0 C ADDxPRS 4862 1.084 0.8538 0.3932
150 8 rs11998620 0 T ADDxPRS 4862 0.9253 -0.8483 0.3963
96 4 rs4691380 0 T ADDxPRS 4862 1.065 0.8151 0.415
102 5 rs6876198 0 C ADDxPRS 4862 1.067 0.7999 0.4238
99 5 rs6886510 0 T ADDxPRS 4862 1.066 0.7934 0.4275
177 13 rs7986895 0 A ADDxPRS 4862 0.938 -0.7827 0.4338
183 13 rs7989842 0 T ADDxPRS 4862 0.9385 -0.7769 0.4372
171 13 rs9523296 0 A ADDxPRS 4862 0.9395 -0.7633 0.4453
120 6 rs12173920 0 T ADDxPRS 4862 0.9028 -0.7587 0.448
138 7 rs7810507 0 A ADDxPRS 4862 1.06 0.7403 0.4591
72 4 rs10023994 0 A ADDxPRS 4862 1.058 0.7383 0.4603
144 7 rs1181729 0 A ADDxPRS 4862 1.064 0.7318 0.4643
87 4 rs6827631 0 C ADDxPRS 4862 1.057 0.7256 0.4681
129 6 rs3800426 0 T ADDxPRS 4862 0.9504 -0.7175 0.4731
84 4 rs1469244 0 G ADDxPRS 4862 1.056 0.7126 0.4761
174 13 rs9515905 0 G ADDxPRS 4862 0.9482 -0.6535 0.5135
75 4 rs17811827 0 T ADDxPRS 4862 1.05 0.6406 0.5218
90 4 rs1364907 0 C ADDxPRS 4862 1.05 0.6377 0.5237
78 4 rs17811863 0 A ADDxPRS 4862 1.048 0.6121 0.5405
81 4 rs17206359 0 G ADDxPRS 4862 1.047 0.5974 0.5502
93 4 rs10017970 0 G ADDxPRS 4862 1.047 0.5927 0.5534
135 7 rs13230111 0 G ADDxPRS 4862 0.9626 -0.5287 0.597
141 7 rs13233731 0 A ADDxPRS 4862 0.9626 -0.5287 0.597
153 9 rs6560613 0 C ADDxPRS 4862 0.9397 -0.4918 0.6229
126 6 rs2049316 0 C ADDxPRS 4862 1.049 0.4438 0.6572
132 7 rs11979110 0 T ADDxPRS 4862 0.969 -0.4355 0.6632
198 20 rs856329 0 T ADDxPRS 4862 0.9679 -0.4057 0.685
180 13 rs7994634 0 T ADDxPRS 4862 0.9682 -0.3944 0.6933
57 3 rs9860730 0 G ADDxPRS 4862 1.027 0.3392 0.7344
48 3 rs2119812 0 T ADDxPRS 4862 0.9533 -0.3231 0.7466
123 6 rs1996913 0 C ADDxPRS 4862 1.039 0.2989 0.765
45 3 rs7613596 0 T ADDxPRS 4862 0.9835 -0.2373 0.8124
159 11 rs2441979 0 G ADDxPRS 4862 0.9821 -0.2329 0.8158
189 18 rs512743 0 C ADDxPRS 4862 1.012 0.1534 0.8781
156 11 rs2513726 0 G ADDxPRS 4862 0.9896 -0.1348 0.8928
114 6 rs9368834 0 G ADDxPRS 4862 0.9871 -0.1093 0.913
195 20 rs6126646 0 T ADDxPRS 4862 1.006 0.07435 0.9407
69 4 rs2139980 0 A ADDxPRS 4862 0.9955 -0.0608 0.9515
111 6 rs3734262 0 T ADDxPRS 4862 1.005 0.04132 0.967
108 5 rs6864348 0 G ADDxPRS 4862 1.003 0.03752 0.9701
21 2 rs2943636 0 G ADDxPRS 4862 0.9987 -0.01831 0.9854

p1.0000e-02

  CHR SNP BP A1 TEST NMISS OR STAT P
165 11 rs2155105 0 T ADDxPRS 4862 0.8667 -1.974 0.04833
3 1 rs7544694 0 G ADDxPRS 4862 1.147 1.781 0.07488
6 1 rs17606320 0 A ADDxPRS 4862 1.146 1.775 0.07587
192 20 rs619289 0 T ADDxPRS 4862 1.193 1.679 0.09321
42 2 rs2673140 0 G ADDxPRS 4862 1.115 1.435 0.1513
9 1 rs7543693 0 T ADDxPRS 4862 1.119 1.423 0.1548
39 2 rs1515099 0 G ADDxPRS 4862 1.113 1.42 0.1555
15 2 rs16982292 0 G ADDxPRS 4862 0.8874 -1.403 0.1605
27 2 rs2943646 0 A ADDxPRS 4862 1.106 1.32 0.1868
36 2 rs2943658 0 A ADDxPRS 4862 1.104 1.311 0.1899
168 12 rs12313737 0 C ADDxPRS 4862 1.102 1.277 0.2016
18 2 rs2943634 0 A ADDxPRS 4862 1.096 1.208 0.2272
30 2 rs2972147 0 T ADDxPRS 4862 1.094 1.18 0.2382
24 2 rs2943640 0 A ADDxPRS 4862 1.087 1.091 0.2755
33 2 rs2972144 0 A ADDxPRS 4862 1.085 1.079 0.2804
177 13 rs7986895 0 A ADDxPRS 4862 0.9196 -1.011 0.3121
60 4 rs6855891 0 T ADDxPRS 4862 1.109 1.008 0.3133
183 13 rs7989842 0 T ADDxPRS 4862 0.9205 -0.9996 0.3175
171 13 rs9523296 0 A ADDxPRS 4862 0.9218 -0.9822 0.326
162 11 rs11236720 0 C ADDxPRS 4862 1.099 0.9689 0.3326
126 6 rs2049316 0 C ADDxPRS 4862 1.108 0.9261 0.3544
138 7 rs7810507 0 A ADDxPRS 4862 1.074 0.8857 0.3758
174 13 rs9515905 0 G ADDxPRS 4862 0.9301 -0.8787 0.3795
159 11 rs2441979 0 G ADDxPRS 4862 0.9327 -0.876 0.381
156 11 rs2513726 0 G ADDxPRS 4862 0.9376 -0.8092 0.4184
96 4 rs4691380 0 T ADDxPRS 4862 1.064 0.7806 0.4351
135 7 rs13230111 0 G ADDxPRS 4862 0.9442 -0.7718 0.4402
141 7 rs13233731 0 A ADDxPRS 4862 0.9442 -0.7718 0.4402
54 3 rs17036328 0 C ADDxPRS 4862 0.9204 -0.7424 0.4579
132 7 rs11979110 0 T ADDxPRS 4862 0.9467 -0.7352 0.4622
186 17 rs17701598 0 A ADDxPRS 4862 1.064 0.7198 0.4716
51 3 rs11709077 0 A ADDxPRS 4862 0.9256 -0.6839 0.494
123 6 rs1996913 0 C ADDxPRS 4862 1.094 0.675 0.4997
66 4 rs1835523 0 G ADDxPRS 4862 1.07 0.6689 0.5036
180 13 rs7994634 0 T ADDxPRS 4862 0.9467 -0.6607 0.5088
63 4 rs11947970 0 T ADDxPRS 4862 1.069 0.6581 0.5105
12 1 rs2065914 0 C ADDxPRS 4862 0.957 -0.6261 0.5312
189 18 rs512743 0 C ADDxPRS 4862 1.046 0.5725 0.567
147 7 rs1181736 0 A ADDxPRS 4862 1.05 0.5627 0.5736
105 5 rs255761 0 T ADDxPRS 4862 1.048 0.5326 0.5943
72 4 rs10023994 0 A ADDxPRS 4862 1.042 0.5295 0.5965
102 5 rs6876198 0 C ADDxPRS 4862 1.044 0.5205 0.6027
99 5 rs6886510 0 T ADDxPRS 4862 1.043 0.5084 0.6112
84 4 rs1469244 0 G ADDxPRS 4862 1.04 0.502 0.6157
87 4 rs6827631 0 C ADDxPRS 4862 1.039 0.4924 0.6225
144 7 rs1181729 0 A ADDxPRS 4862 1.042 0.4752 0.6346
117 6 rs16895362 0 T ADDxPRS 4862 0.9375 -0.4673 0.6403
90 4 rs1364907 0 C ADDxPRS 4862 1.034 0.4227 0.6725
93 4 rs10017970 0 G ADDxPRS 4862 1.033 0.4122 0.6802
120 6 rs12173920 0 T ADDxPRS 4862 0.9546 -0.3346 0.7379
111 6 rs3734262 0 T ADDxPRS 4862 1.041 0.3325 0.7395
108 5 rs6864348 0 G ADDxPRS 4862 1.026 0.3209 0.7483
129 6 rs3800426 0 T ADDxPRS 4862 0.9777 -0.3113 0.7556
45 3 rs7613596 0 T ADDxPRS 4862 0.9798 -0.2864 0.7746
75 4 rs17811827 0 T ADDxPRS 4862 1.022 0.2795 0.7798
78 4 rs17811863 0 A ADDxPRS 4862 1.02 0.2579 0.7965
195 20 rs6126646 0 T ADDxPRS 4862 1.022 0.2557 0.7982
81 4 rs17206359 0 G ADDxPRS 4862 1.019 0.2347 0.8144
69 4 rs2139980 0 A ADDxPRS 4862 0.9866 -0.1776 0.859
114 6 rs9368834 0 G ADDxPRS 4862 1.021 0.1661 0.8681
198 20 rs856329 0 T ADDxPRS 4862 0.9882 -0.1438 0.8857
150 8 rs11998620 0 T ADDxPRS 4862 0.9866 -0.1435 0.8859
57 3 rs9860730 0 G ADDxPRS 4862 1.01 0.1194 0.9049
153 9 rs6560613 0 C ADDxPRS 4862 0.9931 -0.05343 0.9574
48 3 rs2119812 0 T ADDxPRS 4862 1.008 0.05125 0.9591
21 2 rs2943636 0 G ADDxPRS 4862 0.9984 -0.02239 0.9821

p3.0000e-03

  CHR SNP BP A1 TEST NMISS OR STAT P
3 1 rs7544694 0 G ADDxPRS 4862 1.242 2.334 0.01959
6 1 rs17606320 0 A ADDxPRS 4862 1.242 2.332 0.01969
165 11 rs2155105 0 T ADDxPRS 4862 0.8186 -2.297 0.02163
9 1 rs7543693 0 T ADDxPRS 4862 1.195 1.862 0.06266
192 20 rs619289 0 T ADDxPRS 4862 1.22 1.567 0.1171
126 6 rs2049316 0 C ADDxPRS 4862 1.203 1.372 0.17
123 6 rs1996913 0 C ADDxPRS 4862 1.24 1.331 0.1833
42 2 rs2673140 0 G ADDxPRS 4862 1.112 1.157 0.2473
39 2 rs1515099 0 G ADDxPRS 4862 1.11 1.147 0.2514
159 11 rs2441979 0 G ADDxPRS 4862 0.898 -1.118 0.2634
162 11 rs11236720 0 C ADDxPRS 4862 1.139 1.099 0.2718
156 11 rs2513726 0 G ADDxPRS 4862 0.8997 -1.099 0.2719
177 13 rs7986895 0 A ADDxPRS 4862 0.8969 -1.093 0.2745
183 13 rs7989842 0 T ADDxPRS 4862 0.8979 -1.082 0.2792
171 13 rs9523296 0 A ADDxPRS 4862 0.8996 -1.063 0.288
36 2 rs2943658 0 A ADDxPRS 4862 1.1 1.038 0.2994
174 13 rs9515905 0 G ADDxPRS 4862 0.9029 -1.031 0.3024
15 2 rs16982292 0 G ADDxPRS 4862 0.9045 -0.9784 0.3279
138 7 rs7810507 0 A ADDxPRS 4862 1.099 0.9745 0.3298
27 2 rs2943646 0 A ADDxPRS 4862 1.093 0.9703 0.3319
168 12 rs12313737 0 C ADDxPRS 4862 1.091 0.9544 0.3399
135 7 rs13230111 0 G ADDxPRS 4862 0.9182 -0.9535 0.3403
141 7 rs13233731 0 A ADDxPRS 4862 0.9182 -0.9535 0.3403
111 6 rs3734262 0 T ADDxPRS 4862 1.151 0.951 0.3416
132 7 rs11979110 0 T ADDxPRS 4862 0.9186 -0.945 0.3447
18 2 rs2943634 0 A ADDxPRS 4862 1.089 0.9285 0.3531
108 5 rs6864348 0 G ADDxPRS 4862 1.09 0.877 0.3805
69 4 rs2139980 0 A ADDxPRS 4862 0.9255 -0.8553 0.3924
30 2 rs2972147 0 T ADDxPRS 4862 1.081 0.8445 0.3984
180 13 rs7994634 0 T ADDxPRS 4862 0.9194 -0.8442 0.3986
24 2 rs2943640 0 A ADDxPRS 4862 1.081 0.8408 0.4005
114 6 rs9368834 0 G ADDxPRS 4862 1.122 0.774 0.439
33 2 rs2972144 0 A ADDxPRS 4862 1.071 0.7547 0.4505
81 4 rs17206359 0 G ADDxPRS 4862 0.934 -0.7278 0.4667
78 4 rs17811863 0 A ADDxPRS 4862 0.9368 -0.6962 0.4863
75 4 rs17811827 0 T ADDxPRS 4862 0.9374 -0.6893 0.4907
189 18 rs512743 0 C ADDxPRS 4862 1.063 0.6463 0.5181
60 4 rs6855891 0 T ADDxPRS 4862 1.079 0.6261 0.5313
54 3 rs17036328 0 C ADDxPRS 4862 0.924 -0.5892 0.5557
147 7 rs1181736 0 A ADDxPRS 4862 1.059 0.5495 0.5826
144 7 rs1181729 0 A ADDxPRS 4862 1.057 0.5279 0.5976
150 8 rs11998620 0 T ADDxPRS 4862 1.057 0.4929 0.6221
120 6 rs12173920 0 T ADDxPRS 4862 1.087 0.4913 0.6232
51 3 rs11709077 0 A ADDxPRS 4862 0.9382 -0.4705 0.638
117 6 rs16895362 0 T ADDxPRS 4862 1.069 0.3964 0.6918
66 4 rs1835523 0 G ADDxPRS 4862 1.049 0.3964 0.6918
63 4 rs11947970 0 T ADDxPRS 4862 1.047 0.3822 0.7023
90 4 rs1364907 0 C ADDxPRS 4862 0.9674 -0.3519 0.7249
153 9 rs6560613 0 C ADDxPRS 4862 1.057 0.35 0.7263
93 4 rs10017970 0 G ADDxPRS 4862 0.9683 -0.3429 0.7317
87 4 rs6827631 0 C ADDxPRS 4862 0.9687 -0.3402 0.7337
12 1 rs2065914 0 C ADDxPRS 4862 0.973 -0.3228 0.7469
198 20 rs856329 0 T ADDxPRS 4862 0.9691 -0.316 0.752
84 4 rs1469244 0 G ADDxPRS 4862 0.972 -0.3045 0.7608
96 4 rs4691380 0 T ADDxPRS 4862 1.027 0.2844 0.7761
72 4 rs10023994 0 A ADDxPRS 4862 0.9745 -0.2768 0.7819
48 3 rs2119812 0 T ADDxPRS 4862 1.044 0.2352 0.8141
129 6 rs3800426 0 T ADDxPRS 4862 0.9815 -0.2146 0.8301
102 5 rs6876198 0 C ADDxPRS 4862 1.021 0.2051 0.8375
99 5 rs6886510 0 T ADDxPRS 4862 1.021 0.2049 0.8377
186 17 rs17701598 0 A ADDxPRS 4862 1.019 0.1821 0.8555
45 3 rs7613596 0 T ADDxPRS 4862 0.9853 -0.1724 0.8632
21 2 rs2943636 0 G ADDxPRS 4862 1.008 0.09406 0.9251
105 5 rs255761 0 T ADDxPRS 4862 1.009 0.08821 0.9297
57 3 rs9860730 0 G ADDxPRS 4862 0.9928 -0.074 0.941
195 20 rs6126646 0 T ADDxPRS 4862 1.005 0.04663 0.9628

p1.0000e-03

  CHR SNP BP A1 TEST NMISS OR STAT P
165 11 rs2155105 0 T ADDxPRS 4862 0.7659 -2.629 0.008556
6 1 rs17606320 0 A ADDxPRS 4862 1.321 2.546 0.0109
3 1 rs7544694 0 G ADDxPRS 4862 1.32 2.543 0.01098
9 1 rs7543693 0 T ADDxPRS 4862 1.255 2.03 0.04233
123 6 rs1996913 0 C ADDxPRS 4862 1.395 1.75 0.08004
126 6 rs2049316 0 C ADDxPRS 4862 1.271 1.522 0.1279
111 6 rs3734262 0 T ADDxPRS 4862 1.296 1.499 0.1338
69 4 rs2139980 0 A ADDxPRS 4862 0.8606 -1.431 0.1524
192 20 rs619289 0 T ADDxPRS 4862 1.228 1.404 0.1604
108 5 rs6864348 0 G ADDxPRS 4862 1.173 1.395 0.163
114 6 rs9368834 0 G ADDxPRS 4862 1.262 1.338 0.181
81 4 rs17206359 0 G ADDxPRS 4862 0.8646 -1.334 0.1821
78 4 rs17811863 0 A ADDxPRS 4862 0.8678 -1.299 0.1938
75 4 rs17811827 0 T ADDxPRS 4862 0.8679 -1.299 0.1939
174 13 rs9515905 0 G ADDxPRS 4862 0.8686 -1.215 0.2242
177 13 rs7986895 0 A ADDxPRS 4862 0.8685 -1.211 0.226
183 13 rs7989842 0 T ADDxPRS 4862 0.8701 -1.195 0.2323
171 13 rs9523296 0 A ADDxPRS 4862 0.8709 -1.187 0.2352
120 6 rs12173920 0 T ADDxPRS 4862 1.265 1.181 0.2374
117 6 rs16895362 0 T ADDxPRS 4862 1.252 1.135 0.2565
156 11 rs2513726 0 G ADDxPRS 4862 0.883 -1.108 0.2679
159 11 rs2441979 0 G ADDxPRS 4862 0.8852 -1.085 0.278
42 2 rs2673140 0 G ADDxPRS 4862 1.12 1.06 0.2891
39 2 rs1515099 0 G ADDxPRS 4862 1.119 1.051 0.2931
180 13 rs7994634 0 T ADDxPRS 4862 0.885 -1.05 0.2937
132 7 rs11979110 0 T ADDxPRS 4862 0.8977 -1.034 0.301
135 7 rs13230111 0 G ADDxPRS 4862 0.8981 -1.034 0.3013
141 7 rs13233731 0 A ADDxPRS 4862 0.8981 -1.034 0.3013
138 7 rs7810507 0 A ADDxPRS 4862 1.115 0.977 0.3285
36 2 rs2943658 0 A ADDxPRS 4862 1.108 0.9549 0.3396
87 4 rs6827631 0 C ADDxPRS 4862 0.9023 -0.9473 0.3435
90 4 rs1364907 0 C ADDxPRS 4862 0.9027 -0.9367 0.3489
93 4 rs10017970 0 G ADDxPRS 4862 0.9039 -0.9245 0.3552
162 11 rs11236720 0 C ADDxPRS 4862 1.134 0.9108 0.3624
84 4 rs1469244 0 G ADDxPRS 4862 0.9081 -0.8878 0.3746
72 4 rs10023994 0 A ADDxPRS 4862 0.9108 -0.8616 0.3889
150 8 rs11998620 0 T ADDxPRS 4862 1.113 0.8078 0.4192
198 20 rs856329 0 T ADDxPRS 4862 0.9116 -0.8032 0.4218
18 2 rs2943634 0 A ADDxPRS 4862 1.089 0.7944 0.427
27 2 rs2943646 0 A ADDxPRS 4862 1.089 0.7933 0.4276
24 2 rs2943640 0 A ADDxPRS 4862 1.088 0.7803 0.4352
30 2 rs2972147 0 T ADDxPRS 4862 1.077 0.6927 0.4885
33 2 rs2972144 0 A ADDxPRS 4862 1.069 0.6249 0.532
144 7 rs1181729 0 A ADDxPRS 4862 1.079 0.6118 0.5407
54 3 rs17036328 0 C ADDxPRS 4862 0.9112 -0.5935 0.5528
15 2 rs16982292 0 G ADDxPRS 4862 0.9316 -0.5895 0.5555
147 7 rs1181736 0 A ADDxPRS 4862 1.072 0.5637 0.5729
168 12 rs12313737 0 C ADDxPRS 4862 1.054 0.4959 0.62
189 18 rs512743 0 C ADDxPRS 4862 1.056 0.4943 0.6211
153 9 rs6560613 0 C ADDxPRS 4862 1.086 0.4494 0.6531
195 20 rs6126646 0 T ADDxPRS 4862 0.9497 -0.4335 0.6647
60 4 rs6855891 0 T ADDxPRS 4862 1.06 0.4188 0.6754
51 3 rs11709077 0 A ADDxPRS 4862 0.9369 -0.4111 0.681
66 4 rs1835523 0 G ADDxPRS 4862 1.044 0.31 0.7566
63 4 rs11947970 0 T ADDxPRS 4862 1.041 0.287 0.7741
129 6 rs3800426 0 T ADDxPRS 4862 0.9716 -0.2845 0.776
48 3 rs2119812 0 T ADDxPRS 4862 1.046 0.2083 0.835
96 4 rs4691380 0 T ADDxPRS 4862 0.9789 -0.1945 0.8458
21 2 rs2943636 0 G ADDxPRS 4862 1.019 0.1906 0.8488
12 1 rs2065914 0 C ADDxPRS 4862 0.9844 -0.159 0.8737
186 17 rs17701598 0 A ADDxPRS 4862 0.9855 -0.1217 0.9031
45 3 rs7613596 0 T ADDxPRS 4862 0.9883 -0.1171 0.9068
57 3 rs9860730 0 G ADDxPRS 4862 0.9877 -0.1087 0.9134
105 5 rs255761 0 T ADDxPRS 4862 0.9934 -0.05386 0.957
99 5 rs6886510 0 T ADDxPRS 4862 1.006 0.04941 0.9606
102 5 rs6876198 0 C ADDxPRS 4862 1.004 0.03532 0.9718

p3.0000e-04

  CHR SNP BP A1 TEST NMISS OR STAT P
165 11 rs2155105 0 T ADDxPRS 4862 0.7128 -2.931 0.003383
123 6 rs1996913 0 C ADDxPRS 4862 1.654 2.305 0.02115
6 1 rs17606320 0 A ADDxPRS 4862 1.331 2.294 0.02177
3 1 rs7544694 0 G ADDxPRS 4862 1.33 2.289 0.02205
111 6 rs3734262 0 T ADDxPRS 4862 1.519 2.118 0.03414
114 6 rs9368834 0 G ADDxPRS 4862 1.484 1.991 0.04643
9 1 rs7543693 0 T ADDxPRS 4862 1.267 1.857 0.06326
120 6 rs12173920 0 T ADDxPRS 4862 1.498 1.781 0.07491
117 6 rs16895362 0 T ADDxPRS 4862 1.494 1.771 0.07656
126 6 rs2049316 0 C ADDxPRS 4862 1.362 1.718 0.08586
69 4 rs2139980 0 A ADDxPRS 4862 0.8181 -1.684 0.09216
108 5 rs6864348 0 G ADDxPRS 4862 1.242 1.662 0.09647
81 4 rs17206359 0 G ADDxPRS 4862 0.8257 -1.541 0.1234
75 4 rs17811827 0 T ADDxPRS 4862 0.8292 -1.506 0.132
78 4 rs17811863 0 A ADDxPRS 4862 0.8294 -1.504 0.1325
174 13 rs9515905 0 G ADDxPRS 4862 0.8228 -1.475 0.1402
177 13 rs7986895 0 A ADDxPRS 4862 0.8274 -1.426 0.1537
171 13 rs9523296 0 A ADDxPRS 4862 0.829 -1.412 0.1579
183 13 rs7989842 0 T ADDxPRS 4862 0.83 -1.403 0.1605
192 20 rs619289 0 T ADDxPRS 4862 1.248 1.342 0.1795
198 20 rs856329 0 T ADDxPRS 4862 0.8448 -1.292 0.1964
180 13 rs7994634 0 T ADDxPRS 4862 0.8428 -1.289 0.1972
87 4 rs6827631 0 C ADDxPRS 4862 0.8602 -1.22 0.2224
93 4 rs10017970 0 G ADDxPRS 4862 0.8618 -1.195 0.2321
90 4 rs1364907 0 C ADDxPRS 4862 0.8619 -1.194 0.2325
138 7 rs7810507 0 A ADDxPRS 4862 1.163 1.194 0.2326
84 4 rs1469244 0 G ADDxPRS 4862 0.8683 -1.143 0.253
135 7 rs13230111 0 G ADDxPRS 4862 0.8745 -1.141 0.2541
141 7 rs13233731 0 A ADDxPRS 4862 0.8745 -1.141 0.2541
132 7 rs11979110 0 T ADDxPRS 4862 0.8752 -1.13 0.2586
72 4 rs10023994 0 A ADDxPRS 4862 0.8706 -1.122 0.2618
156 11 rs2513726 0 G ADDxPRS 4862 0.88 -0.999 0.3178
39 2 rs1515099 0 G ADDxPRS 4862 1.121 0.9444 0.345
150 8 rs11998620 0 T ADDxPRS 4862 1.154 0.9435 0.3454
159 11 rs2441979 0 G ADDxPRS 4862 0.8869 -0.9368 0.3488
42 2 rs2673140 0 G ADDxPRS 4862 1.119 0.923 0.356
36 2 rs2943658 0 A ADDxPRS 4862 1.109 0.8509 0.3948
195 20 rs6126646 0 T ADDxPRS 4862 0.8935 -0.8355 0.4034
24 2 rs2943640 0 A ADDxPRS 4862 1.09 0.7033 0.4819
18 2 rs2943634 0 A ADDxPRS 4862 1.086 0.6724 0.5014
54 3 rs17036328 0 C ADDxPRS 4862 0.8888 -0.6605 0.5089
27 2 rs2943646 0 A ADDxPRS 4862 1.082 0.6493 0.5162
153 9 rs6560613 0 C ADDxPRS 4862 1.142 0.6354 0.5252
162 11 rs11236720 0 C ADDxPRS 4862 1.102 0.6204 0.535
30 2 rs2972147 0 T ADDxPRS 4862 1.074 0.5857 0.5581
129 6 rs3800426 0 T ADDxPRS 4862 0.9373 -0.5617 0.5743
33 2 rs2972144 0 A ADDxPRS 4862 1.067 0.5316 0.595
60 4 rs6855891 0 T ADDxPRS 4862 1.084 0.5135 0.6076
144 7 rs1181729 0 A ADDxPRS 4862 1.076 0.5076 0.6117
66 4 rs1835523 0 G ADDxPRS 4862 1.077 0.4764 0.6338
96 4 rs4691380 0 T ADDxPRS 4862 0.9428 -0.4739 0.6355
51 3 rs11709077 0 A ADDxPRS 4862 0.9192 -0.4674 0.6402
63 4 rs11947970 0 T ADDxPRS 4862 1.071 0.4412 0.6591
147 7 rs1181736 0 A ADDxPRS 4862 1.064 0.4335 0.6647
15 2 rs16982292 0 G ADDxPRS 4862 0.9496 -0.3741 0.7083
189 18 rs512743 0 C ADDxPRS 4862 1.035 0.2749 0.7834
168 12 rs12313737 0 C ADDxPRS 4862 1.033 0.2675 0.7891
45 3 rs7613596 0 T ADDxPRS 4862 0.9715 -0.2523 0.8008
186 17 rs17701598 0 A ADDxPRS 4862 0.976 -0.1783 0.8585
21 2 rs2943636 0 G ADDxPRS 4862 1.02 0.1725 0.863
48 3 rs2119812 0 T ADDxPRS 4862 1.031 0.1238 0.9015
105 5 rs255761 0 T ADDxPRS 4862 0.9828 -0.1237 0.9016
102 5 rs6876198 0 C ADDxPRS 4862 0.9923 -0.05899 0.953
99 5 rs6886510 0 T ADDxPRS 4862 0.9946 -0.04114 0.9672
12 1 rs2065914 0 C ADDxPRS 4862 1.004 0.03975 0.9683
57 3 rs9860730 0 G ADDxPRS 4862 1.004 0.02804 0.9776

p1.0000e-04

  CHR SNP BP A1 TEST NMISS OR STAT P
165 11 rs2155105 0 T ADDxPRS 4862 0.6541 -3.037 0.00239
123 6 rs1996913 0 C ADDxPRS 4862 1.858 2.344 0.01905
111 6 rs3734262 0 T ADDxPRS 4862 1.706 2.239 0.02513
6 1 rs17606320 0 A ADDxPRS 4862 1.392 2.204 0.02755
3 1 rs7544694 0 G ADDxPRS 4862 1.391 2.197 0.02804
114 6 rs9368834 0 G ADDxPRS 4862 1.659 2.114 0.0345
120 6 rs12173920 0 T ADDxPRS 4862 1.709 1.953 0.05086
117 6 rs16895362 0 T ADDxPRS 4862 1.699 1.934 0.05307
69 4 rs2139980 0 A ADDxPRS 4862 0.7688 -1.827 0.06763
9 1 rs7543693 0 T ADDxPRS 4862 1.307 1.746 0.08074
108 5 rs6864348 0 G ADDxPRS 4862 1.306 1.698 0.0895
81 4 rs17206359 0 G ADDxPRS 4862 0.7852 -1.61 0.1074
174 13 rs9515905 0 G ADDxPRS 4862 0.7766 -1.583 0.1133
75 4 rs17811827 0 T ADDxPRS 4862 0.7897 -1.571 0.1162
78 4 rs17811863 0 A ADDxPRS 4862 0.7896 -1.571 0.1162
126 6 rs2049316 0 C ADDxPRS 4862 1.405 1.569 0.1167
177 13 rs7986895 0 A ADDxPRS 4862 0.7824 -1.532 0.1256
198 20 rs856329 0 T ADDxPRS 4862 0.7856 -1.531 0.1257
171 13 rs9523296 0 A ADDxPRS 4862 0.7835 -1.523 0.1279
183 13 rs7989842 0 T ADDxPRS 4862 0.7861 -1.503 0.1329
180 13 rs7994634 0 T ADDxPRS 4862 0.794 -1.442 0.1493
87 4 rs6827631 0 C ADDxPRS 4862 0.8232 -1.306 0.1916
93 4 rs10017970 0 G ADDxPRS 4862 0.8245 -1.284 0.1993
90 4 rs1364907 0 C ADDxPRS 4862 0.8269 -1.265 0.2061
84 4 rs1469244 0 G ADDxPRS 4862 0.8327 -1.228 0.2194
192 20 rs619289 0 T ADDxPRS 4862 1.274 1.218 0.2233
72 4 rs10023994 0 A ADDxPRS 4862 0.8349 -1.21 0.2261
138 7 rs7810507 0 A ADDxPRS 4862 1.173 1.043 0.2971
135 7 rs13230111 0 G ADDxPRS 4862 0.8625 -1.042 0.2973
141 7 rs13233731 0 A ADDxPRS 4862 0.8625 -1.042 0.2973
132 7 rs11979110 0 T ADDxPRS 4862 0.8632 -1.034 0.3013
195 20 rs6126646 0 T ADDxPRS 4862 0.85 -0.9991 0.3177
39 2 rs1515099 0 G ADDxPRS 4862 1.155 0.9832 0.3255
42 2 rs2673140 0 G ADDxPRS 4862 1.151 0.9569 0.3386
36 2 rs2943658 0 A ADDxPRS 4862 1.14 0.8919 0.3724
54 3 rs17036328 0 C ADDxPRS 4862 0.8266 -0.8856 0.3759
156 11 rs2513726 0 G ADDxPRS 4862 0.8805 -0.8234 0.4103
150 8 rs11998620 0 T ADDxPRS 4862 1.153 0.7788 0.4361
159 11 rs2441979 0 G ADDxPRS 4862 0.8902 -0.7511 0.4526
24 2 rs2943640 0 A ADDxPRS 4862 1.11 0.705 0.4808
51 3 rs11709077 0 A ADDxPRS 4862 0.8634 -0.6756 0.4993
144 7 rs1181729 0 A ADDxPRS 4862 1.121 0.655 0.5125
18 2 rs2943634 0 A ADDxPRS 4862 1.099 0.6389 0.5229
147 7 rs1181736 0 A ADDxPRS 4862 1.111 0.6077 0.5434
129 6 rs3800426 0 T ADDxPRS 4862 0.9189 -0.6055 0.5448
96 4 rs4691380 0 T ADDxPRS 4862 0.9143 -0.5975 0.5502
27 2 rs2943646 0 A ADDxPRS 4862 1.092 0.5966 0.5508
30 2 rs2972147 0 T ADDxPRS 4862 1.084 0.5484 0.5834
153 9 rs6560613 0 C ADDxPRS 4862 1.147 0.5449 0.5858
33 2 rs2972144 0 A ADDxPRS 4862 1.077 0.5016 0.6159
60 4 rs6855891 0 T ADDxPRS 4862 1.088 0.4452 0.6562
45 3 rs7613596 0 T ADDxPRS 4862 0.9407 -0.4406 0.6595
66 4 rs1835523 0 G ADDxPRS 4862 1.084 0.432 0.6657
63 4 rs11947970 0 T ADDxPRS 4862 1.077 0.3969 0.6914
15 2 rs16982292 0 G ADDxPRS 4862 0.9495 -0.3098 0.7567
162 11 rs11236720 0 C ADDxPRS 4862 1.06 0.309 0.7573
21 2 rs2943636 0 G ADDxPRS 4862 1.032 0.2239 0.8228
12 1 rs2065914 0 C ADDxPRS 4862 1.027 0.1972 0.8437
186 17 rs17701598 0 A ADDxPRS 4862 0.981 -0.1159 0.9077
168 12 rs12313737 0 C ADDxPRS 4862 1.015 0.1009 0.9197
189 18 rs512743 0 C ADDxPRS 4862 1.009 0.05996 0.9522
48 3 rs2119812 0 T ADDxPRS 4862 0.9831 -0.05753 0.9541
105 5 rs255761 0 T ADDxPRS 4862 0.9938 -0.03703 0.9705
102 5 rs6876198 0 C ADDxPRS 4862 0.9975 -0.01577 0.9874
57 3 rs9860730 0 G ADDxPRS 4862 0.9987 -0.008143 0.9935
99 5 rs6886510 0 T ADDxPRS 4862 1 0.001199 0.999